From Padua's main station, take local public transport toward Palazzo Bo. Get off at the nearest stop and walk the final few minutes to Palazzo Bo on Via VIII Febbraio. Check the current local connection on the day of travel.
From Orto Botanico di Padova, walk to the nearest public transport stop and travel back to Padua's main station. The departure point is the botanical garden on Via Orto Botanico. Check the current local connection on the day of travel.